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Some Nigerian males across various geographic and socioeconomic strata employ the use of herbals such as Cissus populnea extracts. Cissus populnea (Guill & Perr): A Study of the Aqueous Extract as Potential Spermatogenic Enhancers in Male Wistar Rats. Anthony B. Ojekale, Oladipupo A . Cissus populnea Guill. & Perr. [family VITACEAE]. Herbarium. Royal Botanic Gardens, Kew (K). Collection. Useful Plants of West Tropical Africa. Resource Type.

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Appropriate dilutions of the extract were oxidized with 2. Vitamin C has been reported to contribute to the antioxidant activities of plant food. Testicular histology was well preserved in all animal groups in this study. Analysis of variance and Student’s -test were carried out [ 22 ]. New England Journal of Medicine, Spermatogenesis is adversely affected by oxidative stress, consequent upon an excessive production of reactive Oxygen species ROSor impairment in the antioxidant defense mechanisms [ 43 ].

Some Nigerian males across various geographic and socio-economic strata employ the use of herbals such as Cissus populnea extracts amongst others to manage this and also as herbal aphrodisiacs.

The aqueous extract of stem bark of C. Systems Biology in Reproductive Medicine, Chemicals and Reagents Chemicals and reagents used such as thiobarbituric acid TBA1,phenanthroline, deoxyribose, gallic acid, and Folin-Ciocalteau’s reagent were procured from Sigma-Aldrich, Inc. The vitamin C content of stem bark of C. The percentage content of anthraquinones of the stem bark of Cissus populnea is 1.


Cissus populnea is a plant associated with a myriad of medicinal uses in different parts of the world.

The plant is also used in the treatment of sore breast, indigestion, veneral diseases, intestinal parasites, oedema and eye problems. Thin layer chromatographic plates 10cm by 10cm were cleaned and coated with silica gel G 0.

Vitamin C content of the sample was determined using the method of Benderitter et al. The stem bark has been reported to contain carbohydrates, tannins, cyanogenic glycosides, anthraquinones, saponins, cardiac glycosides and flavonoids Ibrahim, ; Ibrahim et cissu.

Reference Rf Friedrich and Bailer, The counting chamber was charged from this suspension carefully to avoid sperm accumulating in its trough. American Journal of Medical and Biological Research.

Environmental health perspectives, The folkloric use of the aqueous stem bark extract of C. The presence of high concentrations of vitamin C and Zn in C. The plant extract reportedly ameliorated testicular damage induced by flutamide in pre-pubertal rats [ 40 ].

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The high vitamin C content of the plant will definitely contribute additively or synergistically to the observed antioxidant and medicinal properties of the plant. The plant is also used as cathartic, aphrodisiac and antidote to arrow wounds. Sperm count was determined using the improved Neubauer haemocytometer. Traditional Complementary and Alternative Medicines Ayotunde, Ageing, sexuality and enhancement among Yoruba people in south western Nigeria.

View at Google Scholar T. The extraction was carried out as earlier reported cissis 2 ].

Anthraquinones of Cissus Populnea Guill & Perr (Amplidaceae)

Sanda, Effects of aqueous stem bark extract of Cissus populnea on some serum enzymes in normal and alloxan induced diabetic rats. The use of C. The absence of tannins was tested with lead subacetate. Reprod Biol Endocrinol, Interstitium was also normal in all experimental groups with normal Leydig cells visible in many areas Figure 3.


Determination of Epidemical Sperm Parameters Sperm density was determined by modifying a method previously described [ 25 ]. Fenster, Have sperm densities declined? Results The thin layer chromatographic analysis revealed the anthraquinone extracts to contain physcion and chrysaphanol Table 1. It helps the immune system to fight off foreign invaders and tumor cells and supports the cardiovascular system by facilitating fat metabolism and protecting tissues from free radical damage, and it assists the nervous system by converting certain amino acids into neurotransmitters.

Therefore, the higher reducing ability of Cissus populnea extract may have contributed to the higher protective effect observed. Jewo 3Jamiu.

Author information Copyright and License information Disclaimer. There is growing evidence to support global declining fertility in males viz sperm concentration, motility and morphologically normal [ 56789 ]. Oguntola, and Latifat O. Izzo, The aphrodisiac and adaptogenic properties of ginseng.

Sperm of the experimental animals was ciswus, and the parameters count, motility, morphology analysed. Introduction Man since early times had always wanted to leave progenies behind as a means of continuity of his lineage and proof of his procreative ability [ 1 ].